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Semaglutide

1. What are your thought on Wegovy/Ozempic etc for patients who are not necessarily obese but just want to lose a "few pounds?" 2. Is it really a "game changer" for the obese as some people think? 3. What is it like for patients who get off of it with regards to their weight? 4. Does this medication only "work" because it reduces caloric intake or is there another mechanism at play in the brain? Thanks!!

Carninutrients

I consume a vegan diet for environmental and ethical reasons. After 6 years of this diet, I was having noticeable memory/recall issues. I started supplementing choline bitartrate, Coq10, creatine, and taurine and have had much improvement. Is there a scientific basis why this would happen? Are there risks to these supplements? In particular, does choline increase risk because of TMAO? I supposedly have a genetically increased need for choline. Thank you!

Glyphosate

Hi Danny! Glyphosate and GMO foods remain controversial and a source of ‘food fear’ for many. Can you speak to the latest evidence we have on the actual consumption levels of glyphosate in a typical diet and if there is cause for concern at typical intake levels? Thank you for all you do!

Options to lower LDL? Statin data?

Even with a plant based (80%) whole foods diet with low saturated fat and rrgular exercise my cholesterol runs high. I dropped paleo after 5 years and have brought total cholesterol down 50 points to 210 and LDL to 140. No matter what I eat how or much I exercise that seems to be the limit. The data on statins does not look compelling and seems to only really have benefits for those who have already had a heart attack and can tolerate without side effects(interested in your opinion). What do you think and what about red yeast rice and plant sterols. I am 56 with low BMI and excellent diet and metabolic health and take no prescriptions so I am hesitant to. Thanks.

What is the latest scientific opinion on food addiction?

In recent years it has been both suggested that food addiction is a thing by some and is not by others. I know this is an area that researchers continue to look into, but it can be confusing to discern what is the most likely conclusion with the current evidence. It seems that there is probably a reward response that is similar to addiction, and potential maladaptive neuroplasticity in relation to hyper palatable foods, but it would be great to get a clear overview of the current evidence base. thanks Kate