Ask Me Anything

with Sigma Nutrition Premium

Ask a question

Lp(a) and CVD

Hi- there is some interesting data out there on Lp little a and CVD risk and how this measure can be an independent risk factor for CVD and CVD related events. I have very high HDL (well over 120) but according to an NMR test I got, my Lp little a is considered "high." Old school though would say I would live forever with my extremely high HDL but with this Lp(a) being high- I am now really worried. My apo b is moderately high and I have done a CAC scan and that was 0. But from what I understand that Lp(a) being high is what the issue is and that maybe because I am only 40 I have not had any issues. I do not have heart disease in my family/no-one that I know of has had a heart attack. What are your thoughts on Lp(a) as an independent risk factor for CVD/CVD related events? Thanks!

What impact does salt have on bone health?

Salt can impact calcium excretion in the urine and it is said that a high salt diet can increase risk of osteoporosis as it draws calcium from the bone and excretes it. How much of an impact does dietary salt intake actually have on bone health and how high would salt intake have to be for this to be a concern. Obviously high salt intakes are not something to aim for in general, but just wondered if this was a mechanism that could remove meaningful amounts of calcium in a way that I should be advising around this in those that we work with as nutritional professionals. Thanks!

Seed Oils

Sorry if you've covered this before (I'm new to the podcast), but what are your thoughts on the "seed oils as the One True Cause of all human suffering" thing, à la Cate Shanahan, Chris Knobbe, etc.? Seems like a lot of mechanistic speculation with little to no evidence around human outcomes, with some abuse of apparent correlation thrown in for good measure, but I'd love to hear your take. Thanks!