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Why do some SDRIs and serotonin precursors reduce hunger

Why do 5-HTP and Wellbutrin reduce appetite?

Patient Information actual model of obesity

Is there a good simple patient information for healthcare professionals that can be handed to a help seeking patient with obesity in first contact, to have a common ground of evidence based knowledge that the professional as well as the patient can start there journey.

Bacteria, obesity, and the brain

In 2018 a poster was presented at the annual meeting of the Society for Neuroscience titled “The human brain microbiome; there are bacteria in our brains!” which showed bacteria apparently penetrating and inhabiting the cells of healthy human brains. While the work was preliminary, have you heard of any further work in this area? What is your opinion on the possibility that, if bacteria do inhabit the brain, they could play a part in appetite regulation and/or obesity similar to how the gut microbiome can affect our health?

Liposuction effect on leptin and hunger?

When someone undergoes liposuction or other surgery that removes adipose tissue, is there a sudden reduction in leptin levels? While this may reduce leptin resistance, could the drop in leptin lead to increased hunger over time?

Chronic dieting and appetite dysregulation

What is the current research around how chronic energy restriction or following crash diets affects appetite hormones and/ or appetite regulation long term. Is there a physiological mechanism influencing overeating attributable to appetite dysregulation caused by chronic dieting. I ask as this is something I am often tackling in my nutrition consultancy but research in biochemical and physiological mechanisms seems lacking.