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Fish consumption linked with cancer risk

What are your thoughts on the recently released study in the US ( NIH-AARP diet and health study ) linking 2 servings/week, or more. of fish to a 22% increase in risk of developing Skin Cancer. From what I read, the study didn't take into account some key confounders such as history of sun exposure or severe sun burns.

Stephen Guyenet vs. Gary Taubes

I just got through listening to the debate on Joe Rogan between these guys and firstly- clearly Guyenet "won," but I wanted to ask him about whey protein and why didn't he mention how whey protein increases insulin despite it being a protein and not a carbohydrate? If Taubes is all about insulin and carbs/sugars- wouldn't this fact destroy his hypothesis? Additionally I thought that overeating on any macronutrient would increase insulin simply because you are eating food? Also is it possible that both men are correct- that both schools of thought could co-exist and they both be playing a major role in obesity? I loved the debate but was thinking about these 2 things the whole time. Thanks!!

Anorexia and morbid obesity and metabolic compensation

Can you talk about the conditions of anorexia and morbid obesity and how they essentially defy the rules of metabolic compensation? In other words- I understand anorexia to be a mental health condition where the individual starves themselves with a purpose to control weight. And morbid obesity being excessive consumption despite over fatness, etc. If the body has these numerous mechanisms by which calorie restriction or calorie over- consumption results in these compensatory processes-driving us to eat more/less slow us down/speed us up, and many more; do these individuals NOT "hear" these signals or are they just adept at ignoring them or is it that their bodies have lost the ability to compensate for their under or over consumption? Additionally, can anyone become anorexic or morbidly obese or is it merely genetics, and if you are in the proper life circumstance- you set these tendencies off? Thanks so much for your consideration of this convoluted question! Kristen in Dallas.

Visual muscle size differences in plant-based athletes

Hi Sigma team. I'm a coach of a combat sport. Subsequently, I am very aware of my students' weights. Anecdotally, I have noticed a trend in my plant-based students that, when compared to students eating non plant-based diets, there appears an obvious visual difference in muscle sizes (smaller/not as pronounced in plant-based) in individuals of the same weight and approximate height/dimensions. This difference only seems visual, there does not appear to be differences in strength, power, speed etc. Has this been tested/documented/researched anywhere? While I acknowledge these observations might simply be a confirmation bias of mine, if true what might explain this phenomenon? Thanks, Steve.

MPS: Post-exercise vs Rested Conditions

During post exercise conditions does protein ingestion stimulate MPS for longer than the usual 2-3 hour period reported in rested conditions?