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Stephen Guyenet vs. Gary Taubes

I just got through listening to the debate on Joe Rogan between these guys and firstly- clearly Guyenet "won," but I wanted to ask him about whey protein and why didn't he mention how whey protein increases insulin despite it being a protein and not a carbohydrate? If Taubes is all about insulin and carbs/sugars- wouldn't this fact destroy his hypothesis? Additionally I thought that overeating on any macronutrient would increase insulin simply because you are eating food? Also is it possible that both men are correct- that both schools of thought could co-exist and they both be playing a major role in obesity? I loved the debate but was thinking about these 2 things the whole time. Thanks!!

Quantifying Everything

As an iOS developer, my instinct is to assume determinism and quantifiability of the entire universe. I believe this to be fundamentally true. But what is hypothetically possible differs from what we can realistically know. I worry that attempts like yours to quantify some seemingly qualitative measures are doomed. I have similar concerns about happiness research. How do you reassure yourself you can really construct an algorithm that deciphers the "ideal weight program" for any given user - do you rely on averages?

Chronic dieting and appetite dysregulation

What is the current research around how chronic energy restriction or following crash diets affects appetite hormones and/ or appetite regulation long term. Is there a physiological mechanism influencing overeating attributable to appetite dysregulation caused by chronic dieting. I ask as this is something I am often tackling in my nutrition consultancy but research in biochemical and physiological mechanisms seems lacking.

What's Up With Skinny People?

I'm a naturally skinny guy who helps other naturally skinny guys bulk up. I think it largely comes down to a blunted pleasure response to food, smaller stomachs, and/or higher NEAT. A lot of us seem to be taller and more thinly built, too. But why do you think things are things so different for us? Why is it so hard to gain weight? And what can we do about it?

Why do some SDRIs and serotonin precursors reduce hunger

Why do 5-HTP and Wellbutrin reduce appetite?